Ｎ2,Ｎ4-비스(4-(피페라진-1-일)페닐)피리미딘-2,4-디아 민유도체또는이의약학적으로허용가능한염및이를 유효성분으로함유하는암의예방또는치료용약학적 조성물
| 대표분류 | 화학 | ||
|---|---|---|---|
| 연구기관 | 한국화학연구원 | 연구자 | 이광호 |
| 기술내용 |
이전대상 특허번호: 2013-827444(EPO) 이전유형: 양도 기술료: 550만원(부가세포함) 비고: - The present invention relates to a N2,N4-bis(4-(piperazine-1-yl)phenyl)pirimidine-2,4-diamine derivative or a pharmaceutically acceptable salt thereof, and to a composition containing same as an active ingredient for preventing or treating cancer. Since the compound according to the present invention has good effects in inhibiting the activities of anaplastic lymphoma kinase (ALK) and activated Cdc42-associated kinase (ACK1), the compound can have improved therapeutic effects against cancer cells having ALK fusion proteins such as EML4-ALK and NPM-ALK and is expected to be effective in preventing the recurrence of cancer. Therefore, the compound can be effectively used as a composition for preventing or treating cancer. |
||
| 자료집 | 다운로드 | ||